The Board of Regents of the University of Texas System
发明人:
Sean Morrison,Rui Yue
申请号:
US16864872
公开号:
US20200297816A1
申请日:
2020.05.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure describes the C-type lectin CLEC11a as a bone growth factor. Clec11a-deficient mice showed reduced bone volume and mineralization, while bone resorption remained unchanged. Administration of recombinant Clec11a systemically promoted bone formation in mice at risk for osteoporosis.