Prosthetic mitral valve film described herein, which can be used through conduit mitral valve delivery system and technology, to be disposed to connect with the anatomical structure of natural mitral valve formation interface and cooperative anchor. This document describes prosthetic heart valve designs, form interface with natural mitral valve structure and connect to form fluid seal, to minimize mitral reflux and Paravalvular leak. There is also described herein the prosthetic heart valve designs and technology that are used to manage through the blood flow of left ventricular outflow tract. In addition, this document describes the prosthetic heart valve designs and technology that reduce risk of interferences between prosthetic valve and chordae tendineae.
