{4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof, a production method therefor and a pharmaceutical composition for preventing and treating central nervous system disorders containing the same as an active component
Jei Man Ryu;Kwang-Woo Chun;Myung-Hwa Kim;Eui Seok Hong;Jong Soo Chun;Young Seok Byun;Young Il Moon;Heung Mo Kang;Seok Won Kang
发明人:
Seok Won Kang,Jong Soo Chun,Heung Mo Kang,Eui Seok Hong,Kwang-Woo Chun,Young Seok Byun,Myung-Hwa Kim,Young Il Moon,Jei Man Ryu
申请号：
US12990972
公开号：
US08334277B2
申请日:
2009.05.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof, a production method therefor and a pharmaceutical composition for preventing and treating central nervous system disorders which contains the same as an active component. The novel {4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}phosphate or a pharmaceutically acceptable salt thereof according to the present invention can beneficially be used to prevent and treat central nervous system disorders since it exhibits an equivalent biological and pharmacological activity to venlafaxine and salts thereof which are known in the field, it has very little toxicity, and, in particular, it is outstandingly soluble in water as compared with prior-art venlafaxine derivatives.
