PROBLEM TO BE SOLVED: To provide a detection method and a therapeutic method for cancer.SOLUTION: The invention relates to a pharmaceutical composition for the therapy of cancer comprising antibodies against soluble CD155 protein. Monoclonal antibodies are preferable, and chimeric antibodies, human-type antibodies, or humanized antibodies is also preferable. The invention also relates to a detection method of cancer comprising measuring the expression level of soluble CD155 protein or the gene encoding the protein in a biological sample, and associating the measurement result and the possibility of cancer.COPYRIGHT: (C)2015,JPO&INPIT【課題】癌の検出方法及び治療方法の提供。【解決手段】可溶型CD155タンパク質に対する抗体を含む、癌の治療用医薬組成物。好ましくはモノクローナル抗体であり、更にはキメラ抗体、ヒト型化抗体又はヒト化抗体である。生体試料中の可溶型CD155タンパク質又は該タンパク質をコードする遺伝子の発現量を測定し、当該測定結果と癌の可能性とを関連づけることを特徴とする、癌の検出方法。【選択図】なし
