Compounds derived from bridged bicyclic or heterocyclic spiro bicyclic heterocyclic pyprimidines bridged, their methods of preparation and uses, and pharmaceutical composition
JEREMY IAN LEVIN,DARRIN WILLIAM HOPPER,NANCY TORRES,MINU DHANJISH DUTIA,DAN MAARTEN BERGER,XIAOLUN WANG,MARTIN JOSEPH GRANDI,CHUNCHUN ZHANG,ALEJANDRO LEE DUNNICK
申请号:
BRPI0908403
公开号:
BRPI0908403A2
申请日:
2009.02.27
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Compounds of formula A: and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.