YANG, SI YONG,梁时容,梁時容,KIM, JAE WON,金载沅,金載沅,CHO, YOUNG WOOK,赵英郁,趙英郁,KIM, YOUNG SA,金英师,金英師,SHIN, EUN MI,申恩美
申请号：
TW101134620
公开号：
TW201318633A
申请日:
2012.09.20
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention relates to a novel bacteriophage having a specific bactericidal activity against salmonella, a composition for the prevention or treatment of infectious diseases comprising the bacteriophage as an active ingredient, an antibiotic comprising the bacteriophage as an active ingredient, an animal feed or drinking water comprising the bacteriophage as an active ingredient, and a sanitizer or cleaner comprising the bacteriophage as an active ingredient. The novel bacteriophage of the present invention has a specific bactericidal activity against Salmonella choleraesuis, Salmonella typhimurium, Salmonella derby, Salmonella infantis or Salmonella newport with no influences on beneficial bacteria, as well as excellent acid- and heat-resistance and desiccation tolerance. Therefore, the novel bacteriophage can be used for the prevention or treatment of salmonellosis or salmonella food poisoning, which is an infectious disease caused by Salmonella choleraesuis, Salmonella typhimurium, Salmonella derby, Salmonella infantis or Salmonella newport, and also widely used in animal feeds, drinking water for livestock, sanitizers, and cleaners.本發明係有關一種具有針對沙門氏桿菌(salmonella)之專一性殺細菌活性之新穎噬菌體、一種包含該噬菌體作為活性成份供預防或治療傳染性疾病之組成物、一種包含該噬菌體作為活性成份之抗生素、一種包含該噬菌體作為活性成份之動物飼料或飲用水、及一種包含該噬菌體作為活性成份之消毒劑或清潔劑。本發明之新穎噬菌體具有針對豬霍亂沙門氏桿菌(Salmonella choleraesuis)、鼠傷寒沙門氏桿菌(Salmonella typhimurium)、德貝沙門氏桿菌(Salmonella derby)、嬰兒沙門氏桿菌(Salmonella infantis)或新港沙門氏桿菌(Salmonella newport)之專一性殺細菌活性，不會影響有益細菌，且具有極佳之抗酸性與抗熱性，及耐乾性。因此，該新穎噬菌體可用於預防或治療沙門氏桿菌症或沙門氏桿菌食物中毒(其係一種被豬霍亂沙門氏桿菌(Salmonella choleaesuis)、鼠傷寒沙門氏桿菌(Salmonella typhimurium)、德貝沙門氏桿菌(Salmonella derby)、嬰兒沙門氏桿菌(Salmonella infantis)或新港沙門氏桿菌(Salmonella newport)引起之傳染病)，且亦廣泛用於動物飼料、牲畜飲用水、消毒劑及清潔劑。
