PROBLEM TO BE SOLVED: To provides AA targeting compounds which comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody, and various uses of the compounds including methods to treat disorders connected to abnormal angiogenesis.SOLUTION: An anti-angiogenic (AA) targeting agent comprises a peptide comprising a sequence substantially homologous to a specific amino acid sequence. A pharmaceutical composition contains the AA targeting agent. A method for inhibiting or reducing angiogenesis, or for treating or preventing a disease or condition associated with abnormal angiogenesis.COPYRIGHT: (C)2012,JPO&INPIT【課題】抗体中の結合性部位と連結しているAA標的化剤-リンカー複合体を含むAA標的化化合物及び、異常血管形成と関係がある障害を治療するための方法を含む、化合物の様々な使用方法を提供する。【解決手段】特定のアミノ酸配列と実質的に相同の配列を含むペプチドを含む抗血管形成(AA)標的化剤。AA標的化剤を含む、医薬組成物。血管形成を阻害もしくは低減する、または血管形成障害に関連する疾患もしくは症状を治療もしくは予防するための方法。【選択図】なし
