RADU, CAIUS G.,LI, ZHENG,GIPSON, RAYMOND M.,WANG, JUE,SATYAMURTHY, NAGICHETTIAR,LAVIE, ARNON,MURPHY, JENNIFER M.,NATHANSON, DAVID A.,JUNG, MICHAEL E.
申请号：
CA2920738
公开号：
CA2920738A1
申请日:
2014.08.13
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Provided herein are compounds that bind to dCK and methods for treating cancer. Specifically, 2-phenylthiazole derivatives linked to a 4,6-diaminopyrimidine moiety are disclosed as inhibitors of deoxycytidine kinase activity. Inhibitor compounds having a stereo center are also provided. These compounds have therapeutic utility in the treatment of cancer.
