MUCI, ALEX,慕艾利,FINER, JEFFREY T.,费杰瑞,費傑瑞,LU, PU-PING,卢普平,盧普平,RUSSELL, ALAN JAMES,卢思尔,盧思爾,MORGAN, BRADLEY P.,摩尔杰,摩爾傑,MORGANS, JR., DAVID J.,摩杰斯,摩傑斯
申请号：
TW096128335
公开号：
TWI386412B
申请日:
2007.08.02
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasm, post-surgical and post-traumatic muscle weakness, neuromuscular disease, and other indications.提供特定化學品及使用方法，其用於調節骨骼肌肌球蛋白、骨骼肌肌動蛋白、骨骼肌原肌球蛋白、骨骼肌肌鈣蛋白C、骨骼肌肌鈣蛋白I、骨骼肌肌鈣蛋白T及骨骼肌，包括其片段及異構物，以及骨骼肌肌原纖維節，及用於治療肥胖症、肌肉減少症、消耗症候群、虛弱、惡病質、肌肉痙攣、手術後與創傷後肌肉虛弱、神經性肌肉病，以及其它適應症之方法。
