Devices and methods for cleaning an oral cavity by positioning a device suitable for detecting and removing plaque from the surface within the oral cavity having applied thereto a fluorescent agent capable of binding to plaque on the surface. The surface is substantially simultaneously cleaned and irradiated with a light of a wavelength effective to provide a fluorescent emission when contacted with said fluorescent agent. A portion of the fluorescent emission is collected (APV1), and compared to a predetermined threshold value (PPTV). If APV1 is less than PPTV, the device is moved to another section. If APVl is greater than or equal to PPTV, then another portion of fluorescent emission is collected (APV2). The percent reduction from APV1 to APV2 determines when the device is moved to another section.
