Ospedale San Raffaele S.r.l.;Universitá degli Studi di Milano - Bicocca
发明人:
Marco Emilio Bianchi,Maura Casalgrandi,Emilie Joelle Venereau,Silvia Brunelli
申请号:
US14416128
公开号:
US20150203551A1
申请日:
2013.07.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to HMGB1 variants that maintain HMGB1 wild type chemoattractant function while displaying abolished cytokine and/or chemokine stimulating properties. Such molecules are useful in therapy.