Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
发明人:
Seth Pincus,Ryan Craig
申请号：
US14907360
公开号：
US09988438B2
申请日:
2014.07.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Dual variable domain immunoglobulins (DVD Igs) are provided capable of tetravalent binding to bispecific sites of the human immunodeficiency virus (HIV). The DVD Igs may be asymmetric and may have more variable domains on either the light chain or the heavy chain of the Igs. The DVD Igs may have specificity for gp41 and gp120. Therapies are provided using DVD Igs to neutralize HIV viral loads.
