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Stabilized formulations containing anti-Ang2 antibodies
专利权人:
Scott M. Walsh
发明人:
Scott M. Walsh,Daniel B. Dix
申请号:
US13746669
公开号:
US09402898B2
申请日:
2013.01.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides pharmaceutical formulations comprising an antibody that specifically binds to angiopoietin 2 (Ang-2). The formulations may contain, in addition to an anti-Ang-2 antibody, at least one amino acid, at least one sugar, or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months and after being subjected to thermal and other physical stress.
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