SEOUL NATIONAL UNIVERSITY R&;DB FOUNDATION;UNIVERSITY OF ULSAN;KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;PHAROSGEN
发明人:
Youngro Byun,In San Kim,Ahmed Al-Hilal Taslim,Sang-Yoon Kim,Ye Ji Jang
申请号:
US15450272
公开号:
US10501549B2
申请日:
2017.03.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Described herein are doppel-targeting molecules useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (PAH), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.