A composition comprising at least one conjugate prodrug of methylphenidate; Pharmaceutical kit that includes, useful for the treatment of a disease or condition that requires Stimulation of the nervous system such as attention deficit hyperactivity disorder and Depression.
The present technology is directed to prodrugs and compositions for the treatment of various diseases and/or disorders comprising methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof. In some embodiments, the conjugates further include at least one linker. The present technology also relates to the synthesis of methylphenidate, or methylphenidate derivatives, conjugated to at least one alcohol, amine, oxoacid, thiol, or derivatives thereof or combinations thereof.COMPOSICION QUE COMPRENDE UN CONJUGADO DE METILFENIDATO CON NICOTINOILMETILCARBAMATO.