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RECOMBINANT MEASLES VIRUS EXPRESSING CHIKUNGUNYA VIRUS POLYPEPTIDES AND THEIR APPLICATIONS
专利权人:
INSTITUT PASTEUR
发明人:
TANGY, FRÉDÉRIC,BRANDLER ,SAMANTHA,DESPRES ,PHILIPPE,HABEL ,ANDRÉ
申请号:
IN2546DEN2015
公开号:
IN2546DEN2015A
申请日:
2015.03.27
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The invention relates to recombinant Measles virus expressing Chikungunya virus polypeptides and concerns in particular virus like particles (VLP) that contain envelope and capsid proteins of a Chikungunya virus at their surface. These particles are recombinant infectious particles able to replicate in a host after an administration. The invention provides means in particular nucleic acids, vectors , cells and rescue systems to produce these recombinant infectious particles. The invention also relates to the use of these recombinant infectious particles, in particular under the form of a composition , more particularly in a vaccine formulation for the treatment or prevention of an infection by Chikungunya virus.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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