NUNES, JOSEPH J.,MILNE, JILL,BEMIS, JEAN,XIE, ROGER,VU, CHI B.,NG, PUI YEE,DISCH, JEREMY S.
申请号：
PL06789431
公开号：
PL1910384T3
申请日:
2006.08.04
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
Provided herein are novel sirtuin-modulating compounds (XII) and (XIII). The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
