Общество с ограниченной ответственностью "Научно-производственный центр "Амфион" (RU)
发明人:
Артюхов Александр Анатольевич (RU),Штильман Михаил Исаакович (RU),Архипов Антон Борисович (RU),Дементьев Дмитрий Давидович (RU),Наумиди Татьяна Леонидова (RU)
申请号：
RU2014125474/04
公开号：
RU2014125474A
申请日:
2014.06.24
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. The hydrogel material obtained through radical polymerization in a solution containing a mixture of unsaturated derivatives of polyvinyl alcohol of the general formula (1) and unsaturated derivatives of 2-hydroxyethyl starch of formula (II) wherein R is independently selected from -H, -CHCHOH R is -OH R a -O-CO-R, where R- -CHili residue of another acid, which was obtained from polyvinyl alcohol, polyvinyl ether R- unsaturated radical independently selected izCH = CH-CO-O-, CH = C (CH) -CO-O-, CH-CH = CH-CH = CH-CO-O-, CH-CH = CH-CO-O-, CH-CH = CH-CO-O-, CH = C (CH) - CO-O-CH-CH (OH) CH-O-, CH = CH-CO-O-CH- CH (OH) -CH-O-CH = CH-O-, CH = CH-CH-O- iliCH = CH-O-CH-CH-O- are independently selected from -H, -CHCHOH iliRnezavisimo selected from -H , -CHCHOH or -CHCHOCHCHOH are independently selected from -R, -CHCHRili -CHCHOCHCHRn = 85-98 mole%, m = 0-12 mole%, k = 0,5-25 mol%... for unsaturated derivatives of 2- HES general formula (II) ratio of units containing unsaturated radicals is from 0.5 to 95 mol.%. 2. Hydrogel material according to Claim. 1, wherein the ratio between unsaturated derivatives of polyvinyl alcohol, and 2-hydroxyethyl starch is from 99.9 / 0.1 to 0.1 / 99.9 wt.%. 3. Hydrogel material according to claim. 1, characterized in that its formation is carried out in vivo by injecting a solution of polymers of the general formula (I) and (II), further comprising a nontoxic initsiator.4. Hydrogel material according to any one of claims. 1 or 2, characterized in that it is a substrate for cellular inzhenerii.5. Hydrogel material according to any one of claims. 1 or 2, characterized in that it is a drain sredstvom.6. Hydrogel material according to any one of claims. 1-3, characterized in that it is a material for filling soft tissue defects or postoperative polostey.7. hydrogel mother1. Гидрогелевый материал, полученный путем проведения радикальной полимеризации в растворе, содержащем смесь ненасыщенных производных поливинилового спирта общей формулы (1)и
