RICHARDSON CHARLES,BARGATZE ROBERT F.,MENDELMAN PAUL M.
申请号：
NZ62086512
公开号：
NZ620865A
申请日:
2012.07.11
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Disclosed is the use of a vaccine composition comprising genogroup I or genogroup II Norovirus virus-like particles (VLPs) in the manufacture of a medicament for eliciting protective immunity against Norovirus in a human, wherein said genogroup I or genogroup II Norovirus VLPs comprise a capsid protein derived from a genogroup I or genogroup II viral strain, and wherein the medicament is formulated for: (a) administration of no more than a single dose of the vaccine composition； (b) administration parenterally； and (c) inducing at least a three-fold increase in Norovirus-specific serum antibody titer as compared to the titer in the human prior to administration of the medicament.
