PROBLEM TO BE SOLVED: To provide a solid oral dosage form of valsartan of which the formation of the preparation is difficult, and of which the size of each dosage form is large in a conventional method, having a size of the dosage form smaller than that of the conventional one.SOLUTION: The solid oral dosage form having a size smaller than that of a known dosage form containing the valsartan as the active ingredient is produced by molding by a compression method a composition comprising (a) an active ingredient containing the valsartan and optionally hydrochlorothiazide, and (b) pharmaceutically acceptable additives suitable for the preparation of the solid oral dosage form by the compression method.COPYRIGHT: (C)2007,JPO&INPIT【課題】製剤が難しく、従来の方法では各剤形の大きさが大きいバルサルタンにおいて、従来よりも剤形の大きさが小さい固体経口製剤を得る。【解決手段】a)バルサルタンおよび必要に応じてヒドロクロロチアジドを含む活性成分;およびb)圧縮法による固体経口剤形の製造に適当な薬学的に許容される添加剤;を含む組成物を、圧縮法によって成形することによって、バルサルタンを活性成分とする既知の剤形と比べてバルサルタンの量に対する剤形の大きさが小さい固体経口剤形を製造する。【選択図】なし
