INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ.*
发明人:
ALEJANDRO JUÁREZ HERNÁNDEZ
申请号：
MX2011013866
公开号：
MX342931B
申请日:
2011.12.16
申请国别(地区):
MX
年份:
2016
代理人:
摘要：
The present invention refers to a bioprosthesis of bovine pericardium for human use with a support or ring of titanium coated with a textile material, which is resistant, biocompatible and bioimplanted. The bioprosthesis of the present invention reaches a higher valvular area, since the biological tissue is not fixed to the poles of the titanium ring, thus avoiding ruptures, the fixation and sterilization of the biological tissue (bovine pericardium) being performed with a special aldehyde for sterilizing and fixing the tissue intended to align the collagen fibres, increasing the stress strength and the ductility thereof. The bioprosthesis is coupled in order to form a valve similar to the native valve and therefore having a behaviour similar to a natural valve, in such a manner that it is opened in a single direction for preventing the blood volume from escaping. The invention also comprises a method for manufacturing the bioprosthesis where a strategic step of the manufacturing meth od implies treating the bovine tissue with an amino acid solution specific for removing the aldehyde used for the sterilization, this preventing calcium from being adhered to the biological tissue of the prosthesis and delaying the calcification, this means that the amplitude of the valve is not reduced with the use.La presente invención se refiere a una bioprótesis de pericardio bovino para usarse en pacientes humanos con un soporte o anillo de titanio forrado con un material textil, la cual es resiste, biocompatible y bioimplantable. La bioprótesis según la presente invención alcanza una área valvular mucho mayor puesto que el tejido biológico no se fija en la cara interna de los postes del anillo de titanio sino en la cara externa, evitando así posibles rupturas y aumentando el área valvular. La fijación y esterilización del tejido biológico (pericardio bovino) se hace con un aldehído especial para esterilizar y fijar el tejido haciendo que las fibras de colágena se alineen, formánd
