GENENTECH, INC.;CONSTELLATION PHARMACEUTICALS, INC.
发明人:
Marc Adler,Brian K. Albrecht,Sarah Bronner,Kevin X. Chen,Alexandre Côté,Terry Crawford,Patrick Cyr,Jackson Egen,Steven Kauder,Kwong Wah Lai,Jiangpeng Liao,Steven Magnuson,Jeremy Murray,Richard Pastor
申请号：
US15667227
公开号：
US20170333406A1
申请日:
2017.08.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to compounds of formula (I) or formula (II):and to salts thereof, wherein R1-R4 of formula (I) and R1-R3 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.
