DANIEL M. STOREY,LUKE J. RYVES,BARBARA S. KITCHELL
申请号:
US15689340
公开号:
US20180010236A1
申请日:
2017.08.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Nanostructured surfaces on selected substrates are described which are highly resistant to cell adhesion. Such surfaces on medical implants inhibit fibroblast adhesion particularly on nanorough titanium deposited on smooth silicone surfaces. The nanostructured deposited metal coatings can also be engineered so that several cell types, including endothelial, osteoblast, and fibroblast cells, show little if any tendency to attach to the coated surface in vivo.