The objective of the present invention is to provide a tablet which can prevent reduction in content of methotrexate as an active ingredient due to light and production of analogous substances, and prevent misidentification by changing to different color according to every content standard.The present invention provides a methotrexate tablet comprising iron oxide in a film coating layer and a plain tablet, whereby the reduction in content of methotrexate as the active ingredient due to light and production of analogous substances can be suppressed. The methotrexate tablet can guarantee photostability even if it is in light color, therefore it can be made into different color according to every content standard so that it is highly useful in medicine management at medical site or medicine storage at patients residence and the like.本發明之目的為提供一種錠劑,其可防止作為有效成分之胺甲蝶呤因光所致之含量降低及類似物之生成,並且可依含量規格而變成不同顏色從而防止誤認。本發明提供一種胺甲蝶呤錠,其係由於在膜衣層及裸錠中含有氧化鐵,故可抑制作為有效成分之胺甲蝶呤因光所致之含量降低及類似物之生成。該胺甲蝶呤錠即使為淡色,亦可確保光安定性,故可依含量規格而作成不同顏色,於醫療現場之藥劑管理或病患在家中之藥劑保管等方面之有用性高。
