EVANS, Gary Brian,LONGSHAW, Alistair Ian,SCHRAMM, Vern L.,TYLER, Peter
申请号：
ES10800093
公开号：
ES2687168T3
申请日:
2010.07.16
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
The present invention relates to 3-hydroxypyrrolidine compounds of the general formula (I) which are inhibitors of 5-methylthioadenosine phosphorylase or 5-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5-methylthioadenosine phosphorylase or 5-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds.
