CHIMERIC FACTOR H BINDING PROTEINS (FHBP) AND METHODS OF USE

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专利权人:

CHILDRENS HOSPITAL & RESEARCH CENTER AT OAKLAND

发明人:

BEERNINK, PETER,GRANOFF, DAN, M

申请号：

NZ59536110

公开号：

NZ595361A

申请日:

2010.04.29

申请国别(地区):

NZ

年份:

2013

代理人:

摘要：

Patent No. 595361 Disclosed is a non-naturally occurring fHbp, comprising, from N-terminus to C-terminus: VA-I3-VB-I4-VC-I5-VD-I6-VE, wherein the combination of alleles for each of VA, VB, VC, VD, and VE variable segments is not found in Table 7, wherein each of the variable segments is either alpha (a) progenitor sequence or a beta (b) progenitor sequence such as VAADIGAGLADALTAPLDHKDKSLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRDFDIRQLEVDGQLITLESGEFQVYKQSHSALTALQTEQVQDSEDSGKMVAKRQFRIGDIAGEHTSFDKLPKGGSATYRGTAFGSDDAGGKLTYTIDFAAKQGHGKIEHLKSPELNVDLAAAYIKPDEKHH AVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVNGIRHIGLAA.

来源网站：

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