Pharmaceutical composition of solifenacin or salt thereof for use in solid formulation and use of substance with ethylene oxide chain

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专利权人:

ASTELLAS PHARMA INC.

发明人:

SUGIHARA AKIO,YASUJI TAKEHIKO,MASAKI KATSUHIRO,MURAYAMA DAISUKE

申请号：

SK50202011

公开号：

SK50202011U1

申请日:

2005.03.24

申请国别(地区):

SK

年份:

2012

代理人:

摘要：

A solid pharmaceutical preparation of solifenacin or a salt thereof, the preparation being stable and inhibited from decomposing with time when supplied to clinical fields. In a pharmaceutical preparation containing solifenacin or a salt thereof, the compound in an amorphous form was revealed to be causative of cardinal-drug decomposition with time. The composition for a solid pharmaceutical preparation of solifenacin or a salt thereof contains solifenacin or its salt each in a crystalline from, and the content provided are: a process for producing the composition； and a medicinal composition for solid pharmaceutical preparations which contains solifenacin and an amorphization inhibitor.

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