ANDREW S. THOMPSON,DIEDRICH, FALKO,DINARDO, JOSEPH. C.,JAMES ALAN KERSCHEN,LEWIS, JOSEPH, A. II,NEUDECKER, BIRGIT,PETER C WADE,WIELAND, EBERHARD
申请号：
BRPI0920020
公开号：
BRPI0920020A8
申请日:
2009.10.06
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The present invention relates to novel carboxylic acid-substituted idebenone derivatives, skin treatment compositions containing these carboxylic acid-substituted idebenone derivatives, methods of treating skin changes by topical application of these carboxylic acid-substituted idebenone derivatives, and their methods of synthesis. The carboxylic acid-substituted idebenone derivatives of the present invention are unexpectedly effective in treating skin, particularly with respect to skin tolerance. When included in a topical composition, the carboxylic acid-substituted idebenone derivatives of the present invention have an antioxidant effect that is useful in treating a skin change.
