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Process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1H-pyrazol-4-yl)imidazolidine-2,4-diones
专利权人:
SENOMYX; INC.
发明人:
Joseph R. Fotsing
申请号:
US15948282
公开号:
US10412986B2
申请日:
2018.04.09
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to processes and intermediates for the preparation of compounds of formula (I):or a salt or oxide thereof wherein Alk, M1, M2, R1, R2, R3, R4, R5, R6, R7, and n are as described herein.The present invention also relates to compounds of formula (I) and composition comprising a compound of formula (I). Also disclosed is a method of altering or improving the taste of a composition that includes adding to the composition at least one compound of formula (I), in an amount effective to obtain a modified composition having altered or improved taste relative to an otherwise identical composition lacking said compound.
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