Blatt, Lawrence,Seiwert, Scott D.,Beigelman, Leonid,Radhakrishnan, Ramachadran
申请号:
AU2012216834
公开号:
AU2012216834A1
申请日:
2012.09.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012216834A120121004.pdf#####ABSTRACT Disclosed are methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of at least one p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the at least one p38 MAPK by the compound. Also disclosed are derivatives of pirfenidone. These derivatives can modulate a stress activated protein kinase (SAPK) system.WO 2006/122154 PCTIUS2006/01 7988 5/7 aC) C j * ** CS c c 'u4lf53AE (RL 6 qI S ~ TT T WF P 1F'9