Jae-Pyoung Cho,Pung-Sok Lee,Seul-A Lee,Min-Ho Jeong,Mase Lee
申请号:
US14403548
公开号:
US09320718B2
申请日:
2013.05.21
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical composition in multilayer-coated form including an omega-3 fatty acid or an alkyl ester thereof and a statin-based drug, and more particularly, a pharmaceutical composition for oral administration including: (a) a gelatin capsule core containing an omega-3 fatty acid or an alkyl ester thereof; (b) a first coating layer formed by coating, on the gelatin capsule core, hydroxypropyl methylcellulose and a copolymer of butyl methacrylate, (2-demethylaminoeethyl) methacrylate, and methyl methacrylate at a weight ratio of 1:2:1; and (c) a second coating layer formed by coating, on the first coating layer, a coating solution containing a statin-based drug.