Amir Maksyutov,Denis Antonets,Anastasia Bakulina,Rinat Maksyutov
申请号:
US13583439
公开号:
US20130011424A1
申请日:
2011.03.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to immunogenic polyepitope constructs containing CTL and/or Th epitopes and optimized spacer sequences which improve processing and presentation of the epitopes leading to induction of high level of both CD4+ and CD8+ specific T-cell responses and specific types of cytokines, and high level of protection and therapeutic activity.