Substituted pyridines and pryimidines as sodium channel blockers

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专利权人:

Purdue Pharma L.P.

发明人:

Tafesse, Laykea,Yao, Jiangchao

申请号：

AU2013203824

公开号：

AU2013203824A1

申请日:

2013.03.15

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013203824A120131003.pdf#####- 106 Abstract The invention relates to substituted pyridine and pyrimidine compounds of 5 Formula I: Als ,A2 N R1 R2a R2b and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1 , R2a, R2', A', A2, X, and Z are defined as set forth in the specification. 10 The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.

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