An embodiment in accordance with the present invention is directed to a device for fixation, stabilization, and securement of an intravascular cannula to tissue. The fixation device affixes relative to the cannula and cannulated tissue, allowing the needle to be inserted to a shallow depth and then rapidly secured with one motion, using just one hand. The device works to secure cannulae not only in small vessels but also in situations non-permissive to current state-of-the-art cannulas—;such as on wet, adhesive-incompatible surfaces, in intra-operative applications, or when hands-free securement is required. The device can also be utilized to access the umbilical arteries and vein for purposes of placental perfusion for cord blood collection or to facilitate and extend the duration of conventional cord blood collection.