The present invention relates to a method of producing an intermediate necessary for the production of 314d isomer of beraprost in a high yield and in mild reaction conditions. According to the present invention, the method can produce a compound of chemical formula 3 in a high yield, which is a major intermediate necessary for the production of 314d isomer of beraprost, in mild reaction conditions.COPYRIGHT KIPO 2017본 발명은 베라프로스트 314d 이성질체의 제조 중간체를 온화한 반응 조건에서 고수율로 제조하는 방법에 관한 것이다.