Stefan Nilsson,Laura Moro,Giulia Pinton,Arcangela Gabriella Manente
申请号:
US15101132
公开号:
US09974776B2
申请日:
2014.12.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides a treatment of mesothelioma, especially malignant pleural mesothelioma, using an estrogen receptor β subtype (ERβ) agonist, wherein the treatment comprises administering the ERβ agonist to the patient, and then after a time, t, of up to 24 hours administering a platinum-containing anti-cancer drug to the patient. The invention also provides an ERβ agonist and a platinum-containing anti-cancer drug for use in the treatment of mesothelioma in a patient, wherein the treatment comprises administering the ERβ agonist to the patient, and then after a time, t, of up to 24 hours, administering the platinum-containing anti-cancer drug to the patient and a kit comprising a platinum-containing anti-cancer drug and an ERβ agonist.