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TETRALIN ANALOGS HAVING SPHINGOSINE 1-PHOSPHATE AGONIST ACTIVITY
专利权人:
UNIVERSITY OF VIRGINIA PATENT FOUNDATION
发明人:
LYNCH, KEVIN, R,MACDONALD, TIMOTHY, L
申请号:
NZ57689307
公开号:
NZ576893A
申请日:
2007.11.21
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Discloses a 6-octyl-2-tetralone compound or pharmaceutically acceptable salts or ester with the general structure of formula (I). Further discloses the use of the compound for the manufacture of a medicament for treating pathological conditions where the activity of sphingosine 1-phosphate receptors is implicated and agonism of activity is desired. Further discloses the use of the compound for the manufacture of a medicament for treating pathological conditions where the sphingosine 1-phosphate lyase enzyme is implicated and inhibition of the lyase is desired. The disclosed 6-octyl-2-tetralone compound is a sphingosine analog.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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