An infusion adapter for connection with an infusion fluid container, theinfusion adaptercomprising a connection portion configured to engage an injection port of ainfusion fluidcontainer; and a port configured to connect with an intravenous line, the portin fluidcommunication with the connection portion, wherein the connection portionincludes a retainingring extending radially outward from the connection portion, the retainingring is configured tosecurely connect the infusion adapter to the infusion fluid container toresist disconnection of theinfusion adapter from the infusion fluid container once the infusion adapteris connected to theinfusion fluid container, and wherein the retaining ring defines a pluralityof teeth.