Y-type polyethylene glycol modified G-CSF and preparation method and use thereof

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专利权人:

Biosteed Gene Expression Tech. Co.; Ltd.

发明人:

He, Yan,Huang, Shuying,Sun, Li,Deng, Hongyuan,Zheng, Jianhua,Yang, Meihua,Cai, Huili,Wang, Shiyuan,Zhong, Liping,Chen, Ping

申请号：

AU2007363326

公开号：

AU2007363326B2

申请日:

2007.12.29

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Provided are mono-modified granulocyte colony-stimulating factor (G-CSF)by Y-type branched polyethylene glycol at the specific lysine position (Lys17)and the preparation method thereof. The pegylated G-CSF can be used for manufactureof pharmaceutical composition for treating neutropenia induced by infection,leukaemia and chemotherapy etc.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/