Yan Chen;Jie Chen;Jacob Swidorski;Brian Lee Venables;Sing-Yuen Sit;Alicia Regueiro-Ren;Zheng Liu;Ny Sin;Nicholas A. Meanwell
发明人:
Alicia Regueiro-Ren,Zheng Liu,Jacob Swidorski,Ny Sin,Brian Lee Venables,Sing-Yuen Sit,Yan Chen,Jie Chen,Nicholas A. Meanwell
申请号:
US13359727
公开号:
US08846647B2
申请日:
2012.01.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:These compounds are useful for the treatment of HIV and AIDS.