Neutralizing anti-influenza A antibodies and uses thereof

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专利权人:

LLC;MedImmune, LLC;MedImmune;Humabs BioMed SA

发明人:

Benjamin, Ebony,Kallewaard-Lelay, Nicole,McAuliffe, Josephine Mary,Palmer-Hill, Frances,Wachter, Leslie,Yuan, Andy,Zhu, Qing,Corti, Davide,Lanzavecchia, Antonio,Guarino, Barbara,Demarco, Anna

申请号：

AU2014329609

公开号：

AU2014329609A1

申请日:

2014.10.01

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The invention relates to antibodies and binding fragments thereof that are capable of binding to influenza A virus hemagglutinin and neutralizing at least one group 1 subtype and at least 1 group 2 subtype of influenza A virus. In one embodiment, an antibody or binding fragment according to the invention is capable of binding to and/or neutralizing one or more influenza A virus group 1 subtypes selected from H1, H2, H5, H6, H8, H9, H11, H12, H13, H16 and H17 and variants thereof and one or more influenza A virus group 2 subtype selected from H3, H4, H7, H1 0, H14 and H15 and variants thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/