ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES

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专利权人:

GLENMARK PHARMACEUTICALS S.A.

发明人:

ELIAS LAZARIDES,CATHERINE WOODS,MARK BERNARD

申请号：

MYPI 20081636

公开号：

MY147669A

申请日:

2006.11.17

申请国别(地区):

MY

年份:

2012

代理人:

摘要：

237 ABSTRACT ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES THE INVENTION RELATES TO ANTI-CC2 INTEGRIN ANTIBODIES AND THEIR USES. HUMANIZED ANTIBODIES ARE DISCLOSED THAT BIND TO THE 1 5 DOMAIN OF CC2 INTEGRIN AND INHIBIT THE INTERACTION OF A2PL INTEGRIN WITH COLIAGEN. ALSO DISCLOSED ARE THERAPEUTIC USES OF ANTI-A2 INTEGRIN ANTIBODIES IN TREATING (X2OL-MEDIATED DISORDERS, INCLUDING ANTI-A2 INTEGRIN ANTIBODIES THAT BIND TO (X2 INTEGRIN WITHOUT ACTIVATING PLATELETS. 10 (FIG,

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