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ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES
专利权人:
GLENMARK PHARMACEUTICALS S.A.
发明人:
ELIAS LAZARIDES,CATHERINE WOODS,MARK BERNARD
申请号:
MYPI 20081636
公开号:
MY147669A
申请日:
2006.11.17
申请国别(地区):
MY
年份:
2012
代理人:
摘要:
237 ABSTRACT ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES THE INVENTION RELATES TO ANTI-CC2 INTEGRIN ANTIBODIES AND THEIR USES. HUMANIZED ANTIBODIES ARE DISCLOSED THAT BIND TO THE 1 5 DOMAIN OF CC2 INTEGRIN AND INHIBIT THE INTERACTION OF A2PL INTEGRIN WITH COLIAGEN. ALSO DISCLOSED ARE THERAPEUTIC USES OF ANTI-A2 INTEGRIN ANTIBODIES IN TREATING (X2OL-MEDIATED DISORDERS, INCLUDING ANTI-A2 INTEGRIN ANTIBODIES THAT BIND TO (X2 INTEGRIN WITHOUT ACTIVATING PLATELETS. 10 (FIG,
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