SMITHKLINE BEECHAM (CORK) LIMITED;NEUROCRINE BIOSCIENCES, INC.
发明人:
申请号：
EP05818308.8
公开号：
EP1802627B1
申请日:
2005.10.19
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
CRF receptor antagonists are disclosed which may have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in mammals. The CRF receptor antagonists of this invention have the following structure: (I)； and pharmaceutically acceptable salts, esters, solvates, stereoisomers and prodrugs thereof, wherein R1, R2a, R2b, Y, Het, n, o, R6, Ar and R7 are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same.
