The present invention relates to a method of treating multiple myeloma in a subject comprising administering to the subject an amount of (1) a compound of formula (I) as described herein and/or a stereoisomer tautomer or pharmaceutically acceptable salt thereof and an amount of (2) dexamethasone and/or a pharmaceutically acceptable salt solvate metabolite or racemate thereof such that the subject is treated. In another aspect provided herein is a method of treating multiple myeloma in a subject comprising administering to the subject an amount of (1) a compound of formula (I) and an amount of (2) dexamethasone such that the subject is treated pharmaceutical formulations comprising said combination for the treatment of multiple myelom and compositions thereof.
