Rhett Ronald Klein;Donna T. Le;Wei Xu;Wei Cheng;Erick Wang Co;Amy Lew;John M. Nuss;Moon Hwan Kim;William Bajjalieh
发明人:
Wei Cheng,Erick Wang Co,Moon Hwan Kim,Rhett Ronald Klein,Donna T. Le,Amy Lew,John M. Nuss,Wei Xu,William Bajjalieh
申请号:
US10569873
公开号:
US08362017B2
申请日:
2004.08.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.