LASKAVY, VLADISLAV NIKOLAEVICH;IVLEV, ANDREI VALENTINOVICH; VLADISLAV NIKOLAEVICH;LASKAVY
发明人:
LASKAVY, VLADISLAV NIKOLAEVICH
申请号：
CA3018982
公开号：
CA3018982A1
申请日:
2017.06.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention relates to the field of veterinary medicine and can be used for the prophylaxis of bovine leukosis. The invention expands the range of agents available to serve the claimed purpose and gives animals life-long resistance to the leukosis virus. The invention is directed toward solving the problem of broadening the spectrum of prophylactic drugs and developing new approaches to the problem of preventing bovine leukosis, which make it possible to provide animals with life-long resistance to infection by leukosis. The technical result lies in the creation of an agent and a method for the prophylaxis of bovine leukosis, which make it possible to provide a targeted immune response effectively and at little cost by activating cell-mediated immunity to the bovine leukosis virus by increasing the number of killer cells. An agent for the prophylaxis of bovine leukosis contains a water-soluble protein fraction with a molecular mass of 18-20 kDa, isolated from Mycobacterium tuberculosis degradation products and characterized by the presence of peaks at a wavelength of 214 nm in the ultraviolet region of the spectrum, phosphate-buffered saline, an aqueous solution of formic aldehyde, and an isotonic solution of sodium chloride. The proposed method consists in administering said agent to 1-9 day old calves in a single intramuscular dose of 4.0-6.0 ml per head.
