Susan Barnett,Kaustuv Bannerjee,Gillis Otten,Andrew Geall
申请号：
US14410728
公开号：
US20150140068A1
申请日:
2013.06.29
申请国别(地区):
US
年份:
2015
代理人:
摘要：
This invention generally relates to immunogenic compositions that comprise an HIV RNA component and a HIV polypeptide component. Immunogenic compositions that deliver antigenic epitopes in two different forms—a first epitope from human immunodeficiency virus (HIV), in RNA-coded form and a second epitope from HIV, in polypeptide form—are effective in inducing immune response to HIV. The invention also relates to a kit comprising an HIV RNA-based priming composition and an HIV polypeptide-based boosting composition. The kit may be used for sequential administration of the priming and the boosting compositions.
