The present invention relates to a heteroaryl derivative or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition for preventing or treating diseases associated with PI3 kinases, containing the same as an active ingredient. The heteroaryl derivative according to the present invention has an excellent effect of selectively inhibiting PI3 kinases, thereby being useful in preventing or treating PI3 kinase diseases such as: cancers such as hematologic malignancy, ovarian cancer, uterine cervical cancer, breast cancer, colorectal cancer, liver cancer, gastric cancer, pancreatic cancer, colon cancer, peritoneal metastatic cancer, skin cancer, bladder cancer, prostate cancer, lung cancer, osteosarcoma, fibrous tumors, and brain tumors autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosis, multiple sclerosis, diabetes mellitus, hyperthyroidism, myasthenia, Crohns disease, ankylosing spondylitis, autoimmune pernicious anemia, and Sjogrens syndrome and respiratory diseases such as chronic obstructive pulmonary disease (COPD), rhinitis, asthma, chronic bronchitis, chronic pulmonary inflammatory diseases, silicosis, pulmonary sarcoidosis, pleurisy, alveolitis, angitis, pneumatosis, pneumonia, and bronchiectasis.La présente invention concerne un nouveau dérivé hétéroaryle ou un sel pharmaceutiquement acceptable de ce dernier, son procédé de préparation et une composition pharmaceutique destinée à prévenir ou à traiter des maladies associées à des PI3 kinases, le contenant en tant que principe actif. Le dérivé hétéroaryle selon la présente invention a un excellent effet dinhibition sélective des PI3 kinases, étant de ce fait utile dans la prévention ou le traitement de maladies associées à des PI3 kinases telles que : des cancers tels quune tumeur hématologique maligne, le cancer de lovaire, le cancer du col de lutérus, le cancer du sein, le cancer colorectal, le cancer du foie, le cancer de lestomac,
