Pharmaceutical compositions comprising a first anti-acne compound, a second anti-acne compound, and an anti-photoaging compound are described. Methods for the treatment of acne and photoaging using the compositions are also described.L'invention concerne des compositions pharmaceutiques comprenant un premier composé anti-acné, un second composé anti-acné et un composé anti-photovieillissement. L'invention concerne également des procédés de traitement de l'acné et du photovieillissement faisant appel à ces compositions.