MG53 MUTANT AND MUTATION METHOD AND USE THEREOF

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专利权人:

BEIJING BOYALIFE PHARMACEUTICALS LTD.

发明人:

XIAO, RUIPING,CAO, CHUNMEI,ZHANG, YAN,LV, FENGXIANG

申请号：

SG11201505010X

公开号：

SG11201505010XA

申请日:

2014.01.22

申请国别(地区):

SG

年份:

2015

代理人:

摘要：

The invention relates to an MG53 mutant which is a mutant having either one or two or more cysteines of 7 cysteines in an RING structural domain of an N end of MG53 mutated into non-polar amino acids. The MG53 mutant has a prevention/treatment effect and application in protection of hearts and treatment of heart diseases caused by cell death, and especially, the MG53 mutant prevents simultaneously associated insulin resistance, obesity, diabetes and other side effects caused by the MG53 while protecting the hearts.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/